Effect of Anomalous Dynamics on Unbiased Polymer Translocation

نویسندگان

  • Debabrata Panja
  • Gerard T. Barkema
  • Robin C. Ball
چکیده

In this paper, we investigate the microscopic dynamics of a polymer of length N translocating through a narrow pore. Characterization of its purportedly anomalous dynamics has so far remained incomplete. We show that the polymer dynamics is anomalous until the Rouse time τR ∼ N 1+2ν , with a mean square displacement through the pore consistent with t(1+ν)/(1+2ν), with ν ≈ 0.588 the Flory exponent. This is shown to be directly related to a decay in time of the excess monomer density near the pore as t−(1+ν)/(1+2ν) exp(−t/τR). Beyond the Rouse time translocation becomes diffusive. In consequence of this, the dwell-time τd, the time a translocating polymer typically spends within the pore, scales as N2+ν , in contrast to previous claims.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Dynamics of Polymer Translocation: A Short Review with an Introduction of Weakly-Driven Regime

As emphasized in a recent review (by V.V. Palyulin, T. Ala-Nissila, R. Metzler), theoretical understanding of the unbiased polymer translocation lags behind that of the (strongly) driven translocation. Here, we suggest the introduction of a weakly-driven regime, as described by the linear response theory to the unbiased regime, which is followed by the strongly-driven regime beyond the onset of...

متن کامل

Polymer translocation through a nanopore: a showcase of anomalous diffusion.

The translocation dynamics of a polymer chain through a nanopore in the absence of an external driving force is analyzed by means of scaling arguments, fractional calculus, and computer simulations. The problem at hand is mapped on a one-dimensional anomalous diffusion process in terms of the reaction coordinate s (i.e., the translocated number of segments at time t ) and shown to be governed b...

متن کامل

Passage times for unbiased polymer translocation through a narrow pore.

We study the translocation process of a polymer in the absence of external fields for various pore diameters b and membrane thickness L. The polymer performs Rouse and reptation dynamics. The mean translocation time (tau(t)) that the polymer needs to escape from a cell and the mean dwell time (tau(d)) that the polymer spends in the pore during the translocation process obey scaling relations in...

متن کامل

Anomalous dynamics of unbiased polymer translocation through a narrow pore

We consider a polymer of length N translocating through a narrow pore in the absence of external fields. The characterization of its purportedly anomalous dynamics has so far remained incomplete. We show that the polymer dynamics is anomalous up to the Rouse time τR ∼ N1+2ν , with a mean square displacement through the pore consistent with t (1+ν)/(1+2ν), with ν ≈ 0.588 the Flory exponent. This...

متن کامل

Anomalous dynamics of translocation.

We study the dynamics of the passage of a polymer through a membrane pore (translocation), focusing on the scaling properties with the number of monomers N. The natural coordinate for translocation is the number of monomers on one side of the hole at a given time. Commonly used models that assume Brownian dynamics for this variable predict a mean (unforced) passage time tau that scales as N2, e...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2006